
プログラム Program
- Monday, May 12 -
- Tuesday, May 13 -
- Wednesday, May 14 -
- Thursday, May 15 -
12:00-13:00 | Registration |
13:15-13:30 | Welcome Address Yoshio Tateishi (IIAS) |
Opening Remarks Yoshiro Shimura (IIAS) |
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13:30-13:50 | Overview of the International Conference Fuyuki Ishikawa (Kyoto Univ.) |
14:00-16:20 | Session 1 "Telomere and centromere chromatin" Chair Person: Hiroshi Masumoto (Kazusa DNA Research Institute) |
1. Telomere DNA Replication Fuyuki Ishikawa (Kyoto Univ.) |
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2. Centromere specific chromatin structure Tatsuo Fukagawa (National Institute of Genetics) |
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3. Mechanism of Transcriptional Dysregulation in Cornelia de Lange syndrome: Novel insight from Novel Gene Identification Katsuhiko Shirahige (Univ. Tokyo) |
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16:20-17:00 | Plenary Talk1 |
Two stories of chromatin: Epigenetic silencing and telomere function Thomas R. Cech (Univ. Colorado Boulder, USA) |
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17:00-19:00 | Welcome Reception |
9:00-11:40 | Session 2 "Structual aspects of chromatin decoding" Chair Person: Kosuke Morikawa (IIAS) |
1. RNA-protein interactions in the heart of the spliceosome Andy Newman (MRC, UK) |
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2. Decoding of epigenetic status by the maintenace DNA methylation regulator UHRF1 Mariko Ariyoshi (Kyoto Univ.) |
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3. Architecture of an RNA polymerase II transcription pre-initiation complex
Kenji Murakami (Stanford Univ. Medical School, USA) |
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4. Structure and dynamics of the nucleosome isoforms Hitoshi Kurumizaka (Waseda Univ.) |
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11:40-12:20 | Plenary Talk2 |
The nucleosome: Guardian and gateway to the genome Timothy J. Richmond (ETH Zurich, Switzerland) |
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12:20-13:30 | Lunch |
13:30-17:20 | Session 3 "Transcriptional decoding of chromatin" Chair Person: Kazuhiko Igarashi (Tohoku Univ.) |
1. Histone methylation regulation, recognition and link to human disease Yang Shi (Harvard Medical School, USA) |
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2. Epigenetic regulation of mouse sex determination by histone demethylation Makoto Tachibana (Institute for Enzyme Research, Tokushima University) |
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3. Identifying the chromatin looping factors connecting the social genome Mathieu Lupien (Univ. Toronto, Canada) |
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4. Molecular coupling between DNA replication and maintenance DNA methylation Makoto Nakanishi (Nagoya City Univ.) |
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5. A CTD code of RNA polymerase II promotes heterochromatin formation via lncRNA and RNAi. Yota Murakami (Hokkaido Univ.) |
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17:10-18:30 | Poster Session |
18:30-20:00 | Dinner |
9:00-11:20 | Session 4 "Chromatin-RNA interface" Chair Person: Hiroshi Sakamoto (Kobe Univ.) |
1. PIWI-interacting RNA in Drosophila germline; its biogenesis and function Mikiko C. Siomi (Univ. Tokyo) |
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2. Title TBA Yasushi Hiraoka (Osaka Univ.) |
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3. The complex landscape of the chromatinized template affects co-transcriptional mRNA splicing in yeast Christine Guthrie (UCSF, USA) |
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11:20-12:00 | Plenary Talk3 |
Toggling in the spliceosome John Abelson (UCSF, George Beadle Emeritus Professor Caltech, USA) |
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12:00-13:00 | Lunch |
13:00-16:00 | Session 5 "Molecular decoding 1" Chair Person: Yuki Okada (Univ. Tokyo) |
1. Mechanism and function of Tet-mediated dynamic regulation of 5mC Yi Zhang (Harvard Medical School, USA) |
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2. Characterization of non-histone lysine methylation by a synthetic cofactor Yoichi Shinkai (RIKEN) |
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3. Epigenetic Memory: From plasticity to dementia
Andre Fischer (University Medical Center Gottingen, German Center for Neurodegenerative Diseases (DZNE), Germany) |
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15:10-15:30 | Short Talk 1 |
15:30-15:50 | Coffee Break |
15:50-18:00 | Session 6 "Molecular decoding 2" Chair Person: Makoto Tachibana (Univ. Tokushima) |
1. Role of heterochromatin protein 1 in higher-order chromatin assembly Jun-ichi Nakayama (Nagoya City Univ.) |
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2. Epigenetics and dynamics of non-coding genome Kunihiro Ohta (Univ. Tokyo) |
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3. Condensin is a critical organizer of the functional genome Ken-ichi Noma (The Wistar Institute, USA) |
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18:00-18:20 | Short Talk 2 |
18:20-20:00 | Dinner |
9:00-11:50 | Session 7 "Extended phenotypes of chromatin" Chair Person: Kunihiro Ohta (Univ. Tokyo) |
1. Transcriptional regulation driving megakaryocyte maturation and platelet production Hozumi Motohashi (Tohoku Univ.) |
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2. Epigenetic regulation of hematopoietic stem cells Atsushi Iwama (Chiba Univ.) |
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3. Computational epigenomics in cancer and aging Wei Li (Dan L. Duncan Cancer Center, USA) |
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4. Oscillatory gene expression in somitogenesis and neurogenesis Ryuichiro Kageyama (Kyoto Univ.) |
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12:00-12:15 | Concluding Remarks Kosuke Morikawa (IIAS) |