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プログラム Program

プログラム
- Monday, May 12 -
12:00-13:00 Registration
13:15-13:30 Welcome Address
Yoshio Tateishi (IIAS)
Opening Remarks
Yoshiro Shimura (IIAS)
13:30-13:50 Overview of the International Conference
Fuyuki Ishikawa (Kyoto Univ.)
14:00-16:20 Session 1 "Telomere and centromere chromatin"
Chair Person: Hiroshi Masumoto (Kazusa DNA Research Institute)
1. Telomere DNA Replication
Fuyuki Ishikawa (Kyoto Univ.)
2. Centromere specific chromatin structure
Tatsuo Fukagawa (National Institute of Genetics)
3. Mechanism of Transcriptional Dysregulation in Cornelia de Lange syndrome: Novel insight from Novel Gene Identification
Katsuhiko Shirahige (Univ. Tokyo)
16:20-17:00 Plenary Talk1
Two stories of chromatin: Epigenetic silencing and telomere function
Thomas R. Cech (Univ. Colorado Boulder, USA)
17:00-19:00 Welcome Reception
- Tuesday, May 13 -
9:00-11:40 Session 2 "Structual aspects of chromatin decoding"
Chair Person: Kosuke Morikawa (IIAS)
1. RNA-protein interactions in the heart of the spliceosome
Andy Newman (MRC, UK)
2. Decoding of epigenetic status by the maintenace DNA methylation regulator UHRF1
Mariko Ariyoshi (Kyoto Univ.)
3. Architecture of an RNA polymerase II transcription pre-initiation complex
Kenji Murakami (Stanford Univ. Medical School, USA)
4. Structure and dynamics of the nucleosome isoforms
Hitoshi Kurumizaka (Waseda Univ.)
11:40-12:20 Plenary Talk2
The nucleosome: Guardian and gateway to the genome
Timothy J. Richmond (ETH Zurich, Switzerland)
12:20-13:30 Lunch
13:30-17:20 Session 3 "Transcriptional decoding of chromatin"
Chair Person: Kazuhiko Igarashi (Tohoku Univ.)
1. Histone methylation regulation, recognition and link to human disease
Yang Shi (Harvard Medical School, USA)
2. Epigenetic regulation of mouse sex determination by histone demethylation
Makoto Tachibana (Institute for Enzyme Research, Tokushima University)
3. Identifying the chromatin looping factors connecting the social genome
Mathieu Lupien (Univ. Toronto, Canada)
4. Molecular coupling between DNA replication and maintenance DNA methylation
Makoto Nakanishi (Nagoya City Univ.)
5. A CTD code of RNA polymerase II promotes heterochromatin formation via lncRNA and RNAi.
Yota Murakami (Hokkaido Univ.)
17:10-18:30 Poster Session
18:30-20:00 Dinner
- Wednesday, May 14 -
9:00-11:20 Session 4 "Chromatin-RNA interface"
Chair Person: Hiroshi Sakamoto (Kobe Univ.)
1. PIWI-interacting RNA in Drosophila germline; its biogenesis and function
Mikiko C. Siomi (Univ. Tokyo)
2. Title TBA
Yasushi Hiraoka (Osaka Univ.)
3. The complex landscape of the chromatinized template affects co-transcriptional mRNA splicing in yeast
Christine Guthrie (UCSF, USA)
11:20-12:00 Plenary Talk3
Toggling in the spliceosome
John Abelson (UCSF, George Beadle Emeritus Professor Caltech, USA)
12:00-13:00 Lunch
13:00-16:00 Session 5 "Molecular decoding 1"
Chair Person: Yuki Okada (Univ. Tokyo)
1. Mechanism and function of Tet-mediated dynamic regulation of 5mC
Yi Zhang (Harvard Medical School, USA)
2. Characterization of non-histone lysine methylation by a synthetic cofactor
Yoichi Shinkai (RIKEN)
3. Epigenetic Memory: From plasticity to dementia
Andre Fischer (University Medical Center Gottingen, German Center for Neurodegenerative Diseases (DZNE), Germany)
15:10-15:30 Short Talk 1
15:30-15:50 Coffee Break
15:50-18:00 Session 6 "Molecular decoding 2"
Chair Person: Makoto Tachibana (Univ. Tokushima)
1. Role of heterochromatin protein 1 in higher-order chromatin assembly
Jun-ichi Nakayama (Nagoya City Univ.)
2. Epigenetics and dynamics of non-coding genome
Kunihiro Ohta (Univ. Tokyo)
3. Condensin is a critical organizer of the functional genome
Ken-ichi Noma (The Wistar Institute, USA)
18:00-18:20 Short Talk 2
18:20-20:00 Dinner
- Thursday, May 15 -
9:00-11:50 Session 7 "Extended phenotypes of chromatin"
Chair Person: Kunihiro Ohta (Univ. Tokyo)
1. Transcriptional regulation driving megakaryocyte maturation and platelet production
Hozumi Motohashi (Tohoku Univ.)
2. Epigenetic regulation of hematopoietic stem cells
Atsushi Iwama (Chiba Univ.)
3. Computational epigenomics in cancer and aging
Wei Li (Dan L. Duncan Cancer Center, USA)
4. Oscillatory gene expression in somitogenesis and neurogenesis
Ryuichiro Kageyama (Kyoto Univ.)
12:00-12:15 Concluding Remarks
Kosuke Morikawa (IIAS)